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MSN Exam for Anticoagulants (PM)
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Question 1
Which of the following is an advantage of low molecular weight heparin (LMWH) over unfractionated heparin?
A
Has a greater bioavailibility
B
Does not require monitoring of activated partial thromboplastin time
C
Given subcutaneously therefore can be administered in “out of hospital setting”
D
All of the above
Question 2
What is the most acceptable frequency of INR monitoring in a patient taking warfarin?
A
Initially twice daily, then daily, then weekly, and then monthly
B
Initially twice per week, then weekly, then every two or three weeks, and then monthly
C
Initially daily, then weekly, and then monthly
D
Initially thrice daily, then twice daily, then daily, then weekly, and then monthly
Question 3
What is the value of International normalized ratio (INR) above which warfarin does not provide any additional therapeutic benefit in most patients, but is associated with a higher risk of bleeding?
A
3.5
B
4.0
C
2.5
D
3.0
Question 4
Time taken for observable anticoagulant effect of warfarin is:
A
2-7 days
B
8-10 days
C
24-36 hours
D
6-12 hours
Question 5
Which of the following is correct with regard to patients taking warfarin undergoing surgery with minimal risk of bleeding?
A
Switch over to heparin seven days prior to surgery and restart warfarin after surgery
B
Do not stop warfarin but check INR prior to surgery
C
Switch over to heparin five days prior to surgery and restart warfarin after surgery
D
Switch over to heparin two days prior to surgery and restart warfarin after surgery
Question 6
Low molecular weight heparins (LMWHs) do not require monitoring, but when necessary, which of the following is measured?
A
Activated partial thromboplastin time (APTT)
B
Anti-factor Xa level
C
Thrombin time
D
Prothrombin time
Question 7
Which of the following sentence is true with regard to warfarin?
A
Binds to antithrombin III
B
Is a thrombin inhibitor
C
Is a vitamin K antagonist
D
Activates fibrinolysis
Question 8
Which of the following anticoagulant should not be given during pregnancy?
A
Warfarin
B
Unfractionated heparin
C
Low molecular weight heparins (LMWHs)
D
All of the above
Question 9
Which of the following is not an approved indication for warfarin therapy?
A
Peripheral artery disease
B
Atrial fibrillation
C
Heart valve replacement
D
Deep vein thrombosis
Question 10
Which of the following is used for reversal of anticoagulant effect of warfarin in case of life-threatening bleeding?
A
Any of the above
B
Vitamin K or Vitamin K dependant coagulation factors
C
Platelets
D
Protamine
Question 11
Which of the following statement(s) concerning heparin is/are true?
A
All of the above
B
It binds to antithrombin III leading to anticoagulant effect
C
Heparin therapy is monitored with activated partial thromboplastin time (APTT)
D
It exhibits varying anticoagulant response
Question 12
Which of the following is the recommended test to monitor the effect of oral anticoagulant therapy?
A
Thrombin time
B
International normalized ratio (INR)
C
Partial thromboplastin time (PTT)
D
Bleeding time
Question 13
The anticoagulant effect of heparin is rapidly reversed with:
A
Platelets
B
Packed red blood cells
C
Infusion of vitamin K dependant coagulation factors
D
Protamine
Question 14
Anticoagulants are indicated for an indefinite period in patients with:
A
High risk of myocardial infarction
B
All of the above
C
Atrial fibrillation
D
Venous thromboembolism
Question 15
Anticoagulation in warfarin users at high risk of thromboembolism, undergoing surgery associated with high risk of bleeding involves:
A
All of the above
B
Restart regular warfarin therapy after surgery once adequate haemostasis is achieved
C
Start with full dose unfractionated heparin or LMWH 2-3 days preoperatively
D
Stop warfarin 4-5 days prior to surgery
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MSN Exam for Anticoagulants (EM)
Choose the letter of the correct answer. You got 15 minutes to finish the exam .Good luck!
Start
Congratulations - you have completed MSN Exam for Anticoagulants (EM).
You scored %%SCORE%% out of %%TOTAL%%.
Your performance has been rated as %%RATING%%
Your answers are highlighted below.
Question 1
Which of the following is correct with regard to patients taking warfarin undergoing surgery with minimal risk of bleeding?
A
Switch over to heparin five days prior to surgery and restart warfarin after surgery
B
Switch over to heparin two days prior to surgery and restart warfarin after surgery
C
Do not stop warfarin but check INR prior to surgery
D
Switch over to heparin seven days prior to surgery and restart warfarin after surgery
Question 2
Which of the following statement(s) concerning heparin is/are true?
A
It exhibits varying anticoagulant response
B
All of the above
C
It binds to antithrombin III leading to anticoagulant effect
D
Heparin therapy is monitored with activated partial thromboplastin time (APTT)
Question 3
Which of the following sentence is true with regard to warfarin?
A
Binds to antithrombin III
B
Is a thrombin inhibitor
C
Is a vitamin K antagonist
D
Activates fibrinolysis
Question 4
Which of the following is not an approved indication for warfarin therapy?
A
Peripheral artery disease
B
Deep vein thrombosis
C
Heart valve replacement
D
Atrial fibrillation
Question 5
The anticoagulant effect of heparin is rapidly reversed with:
A
Infusion of vitamin K dependant coagulation factors
B
Platelets
C
Packed red blood cells
D
Protamine
Question 6
Low molecular weight heparins (LMWHs) do not require monitoring, but when necessary, which of the following is measured?
A
Activated partial thromboplastin time (APTT)
B
Thrombin time
C
Prothrombin time
D
Anti-factor Xa level
Question 7
Which of the following is an advantage of low molecular weight heparin (LMWH) over unfractionated heparin?
A
Does not require monitoring of activated partial thromboplastin time
B
Has a greater bioavailibility
C
All of the above
D
Given subcutaneously therefore can be administered in “out of hospital setting”
Question 8
What is the value of International normalized ratio (INR) above which warfarin does not provide any additional therapeutic benefit in most patients, but is associated with a higher risk of bleeding?
A
4.0
B
3.5
C
2.5
D
3.0
Question 9
Anticoagulants are indicated for an indefinite period in patients with:
A
High risk of myocardial infarction
B
All of the above
C
Venous thromboembolism
D
Atrial fibrillation
Question 10
Time taken for observable anticoagulant effect of warfarin is:
A
8-10 days
B
6-12 hours
C
2-7 days
D
24-36 hours
Question 11
Anticoagulation in warfarin users at high risk of thromboembolism, undergoing surgery associated with high risk of bleeding involves:
A
Start with full dose unfractionated heparin or LMWH 2-3 days preoperatively
B
Stop warfarin 4-5 days prior to surgery
C
All of the above
D
Restart regular warfarin therapy after surgery once adequate haemostasis is achieved
Question 12
Which of the following is the recommended test to monitor the effect of oral anticoagulant therapy?
A
International normalized ratio (INR)
B
Bleeding time
C
Partial thromboplastin time (PTT)
D
Thrombin time
Question 13
What is the most acceptable frequency of INR monitoring in a patient taking warfarin?
A
Initially thrice daily, then twice daily, then daily, then weekly, and then monthly
B
Initially twice per week, then weekly, then every two or three weeks, and then monthly
C
Initially daily, then weekly, and then monthly
D
Initially twice daily, then daily, then weekly, and then monthly
Question 14
Which of the following is used for reversal of anticoagulant effect of warfarin in case of life-threatening bleeding?
A
Vitamin K or Vitamin K dependant coagulation factors
B
Platelets
C
Protamine
D
Any of the above
Question 15
Which of the following anticoagulant should not be given during pregnancy?
A
All of the above
B
Unfractionated heparin
C
Low molecular weight heparins (LMWHs)
D
Warfarin
Once you are finished, click the button below. Any items you have not completed will be marked incorrect.
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There are 15 questions to complete.
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8
9
10
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13
14
15
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question
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Question Details
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Question Text
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Text Mode
Text Mode – Text version of the exam
1. Anticoagulants are indicated for an indefinite period in patients with:
Atrial fibrillation
Venous thromboembolism
High risk of myocardial infarction
All of the above
2. Which of the following sentence is true with regard to warfarin?
Is a vitamin K antagonist
Is a thrombin inhibitor
Activates fibrinolysis
Binds to antithrombin III
3. Which of the following is not an approved indication for warfarin therapy?
Atrial fibrillation
Heart valve replacement
Deep vein thrombosis
Peripheral artery disease
4. Time taken for observable anticoagulant effect of warfarin is:
6-12 hours
24-36 hours
2-7 days
8-10days
5. Which of the following is the recommended test to monitor the effect of oral anticoagulant therapy?
Thrombin time
International normalized ratio (INR)
Bleeding time
Partial thromboplastin time (PTT)
6. What is the most acceptable frequency of INR monitoring in a patient taking warfarin?
Initially thrice daily, then twice daily, then daily, then weekly, and then monthly
Initially twice daily, then daily, then weekly, and then monthly
Initially daily, then weekly, and then monthly
Initially twice per week, then weekly, then every two or three weeks, and then monthly
7. What is the value of International normalized ratio (INR) above which warfarin does not provide any additional therapeutic benefit in most patients, but is associated with a higher risk of bleeding?
4.0
3.5
3.0
2.5
8. Which of the following is used for reversal of anticoagulant effect of warfarin in case of life-threatening bleeding?
Platelets
Protamine
Vitamin K or Vitamin K dependant coagulation factors
Any of the above
9. Which of the following statement(s) concerning heparin is/are true?
It binds to antithrombin III leading to anticoagulant effect
It exhibits varying anticoagulant response
Heparin therapy is monitored with activated partial thromboplastin time (APTT)
All of the above
10. Which of the following is an advantage of low molecular weight heparin (LMWH) over unfractionated heparin?
Does not require monitoring of activated partial thromboplastin time
Has a greater bioavailibility
Given subcutaneously therefore can be administered in “out of hospital setting”
All of the above
11. Low molecular weight heparins (LMWHs) do not require monitoring, but when necessary, which of the following is measured?
Anti-factor Xa level
Thrombin time
Prothrombin time
Activated partial thromboplastin time (APTT)
12. The anticoagulant effect of heparin is rapidly reversed with:
Protamine
Infusion of vitamin K dependant coagulation factors
Packed red blood cells
Platelets
13. Which of the following anticoagulant should not be given during pregnancy?
Warfarin
Low molecular weight heparins (LMWHs)
Unfractionated heparin
All of the above
14. Which of the following is correct with regard to patients taking warfarin undergoing surgery with minimal risk of bleeding?
Do not stop warfarin but check INR prior to surgery
Switch over to heparin two days prior to surgery and restart warfarin after surgery
Switch over to heparin five days prior to surgery and restart warfarin after surgery
Switch over to heparin seven days prior to surgery and restart warfarin after surgery
15. Anticoagulation in warfarin users at high risk of thromboembolism, undergoing surgery associated with high risk of bleeding involves:
Stop warfarin 4-5 days prior to surgery
Start with full dose unfractionated heparin or LMWH 2-3 days preoperatively
Restart regular warfarin therapy after surgery once adequate haemostasis is achieved
All of the above
Answers
A. Atrial fibrillation
A. Is a vitamin K antagonist
D. Peripheral artery disease
C. 2-7 days
B. International normalized ratio (INR)
D. Initially twice per week, then weekly, then every two or three weeks, and then monthly
A. 4.0
C. Vitamin K or Vitamin K dependant coagulation factors
D. All of the above
D. All of the above
A. Anti-factor Xa level
A. Protamine
A. Warfarin
A. Do not stop warfarin but check INR prior to surgery