Practice Mode– Questions and choices are randomly arranged, the answer is revealed instantly after each question, and there is no time limit for the exam.
NCLEX Practice Exam for Pharmacology Essential Principles and Drug Administration (PM)
Choose the answer of the correct answer. Good luck!
Start
Congratulations - you have completed NCLEX Practice Exam for Pharmacology Essential Principles and Drug Administration (PM).
You scored %%SCORE%% out of %%TOTAL%%.
Your performance has been rated as %%RATING%%
Your answers are highlighted below.
Question 1
When a drug is 50% protein bound, it means that:
A
50% of the drug destroys protein
B
50% of the dose is at work
C
50% of the drug is excreted in the kidneys
D
Protein must be restricted in the diet
Question 1 Explanation:
The percentage of drug NOT protein bound is the amount of drug that is free to exert its effect on the body’s issues. A, C, and D are incorrect because protein binding has nothing to do with the destruction of protein, drug excretion, or protein in the diet. Note that the concept of “50% bound” literally means that 50% is BOUND or connected to protein. This means that the remaining 50% is available.
Question 2
An unexpected effect of the drug is known as a(n):
A
Side effect
B
Adverse effect
C
Toxic reaction
D
Allergic reaction
Question 2 Explanation:
An adverse reaction is a harmful and unexpected reaction. A side effect is expected and predictable. C and D are incorrect because a toxic reaction is a type of adverse reaction.
Question 3
When performing an assessment about medication, the drug history should include:
A
Complete vital signs
B
Client’s goal of therapy
C
Reason for medication
D
Administration of OTC medications
Question 3 Explanation:
The nurse should determine if the client is taking any other medications, especially OTC medications because their effects are often minimized. Other choices are important part of assessment, but choice D is the most accurate answer.
Question 4
Distribution is affected by:
A
Biotransformation
B
Excretion
C
Protein binding
D
Lipid binding
Question 4 Explanation:
Distribution depends on protein binding as well as circulation. Biotransformation is the act of metabolizing the drug. Excretion describes the act of eliminating the drug. There is no such thing as lipid binding.
Question 5
Absorption, distribution, and excretion may be increased by which of the following diseases?
A
Hyperthyroidism
B
Renal insufficiency
C
Liver disease
D
Hypothyroidism
Question 5 Explanation:
Diseases that speed up metabolism, such as hyperthyroidism, will increase absorption, distribution, and elimination. B, C, and D are incorrect because diseases that decrease metabolism, such as hypothyroidism, renal insufficiency, and liver disease, will slow these metabolic processes.
Question 6
The name selected by the original manufacturer based on the chemical structure of the drug is the:
A
Chemical name
B
Drug name
C
Generic name
D
Trade name
Question 6 Explanation:
The chemical name is the chemical name is the chemical structure of the compound. The trade name is a proprietary name owned by the company that creates and registers it. The drug name does not exist.
Question 7
Safety of a drug is determined by the degree between:
A
Therapeutic and toxic doses
B
Potency and efficacy
C
Subtherapeutic and toxic levels
D
Side and adverse effects
Question 7 Explanation:
Safety is determined by the degree between therapeutic and toxic doses. Potency and efficacy are not related to safety. Subtherapeutic levels are not part of safety determinations because if a drug is subtherapeutic it does not exert any desired effect. Side effects are expected, and adverse effects are often the result of toxicity.
Question 8
Which of the following will determine nursing interventions for a client on medication?
A
Assessment
B
Diagnoses
C
Implementation
D
Evaluation
Question 8 Explanation:
The nursing diagnosis is the conclusion derived from the assessment, and it is the component of the nursing process that drives the interventions.
Question 9
When two drugs given together have an effect equal to the sum of their respective effects, the interaction is known as:
A
Potentiated
B
Antagonized
C
Agonist
D
Additive
Question 9 Explanation:
An addictive effect occurs when two drugs are given together and their effects is equal to the sum of their respective effects.
Question 10
Which of the following muscles is a possible site for IM injections?
A
Outer aspect of the hip
B
Shoulder
C
Vastus gluteus
D
Vastus lateralis
Question 10 Explanation:
Possible injection sites for IM administration include ventrogluteal, deltoid, dorsogluteal, vastus lateralis, and rectus femoris.
Question 11
When performing an assessment to determine which medications can be used, which of the following elements is most important?
A
Physical examination
B
Allergies
C
Presence of illness
D
Weight
Question 11 Explanation:
Allergies must be determined so that the nurse does not administer a drug that would be dangerous to the client.
Question 12
The extent to which drug is absorbed and transported to target tissue is known as:
A
Steady-state accumulation
B
Therapeutic drug levels
C
Bioavailability
D
Distribution
Question 12 Explanation:
Bioavailability is the extent to which a drug is absorbed and transported to target tissue. Steady-state accumulation means that the amount of drug present is sufficient to exert its therapeutic effect. Therapeutic drug levels are serum blood tests used to measure the amount of circulating drug present. Distribution is the process by which drugs are transported to tissues.
Question 13
When deciding on what time of day to give medications, the nurse pays closest attention to the client’s habits regarding:
A
Eating
B
Sleeping
C
Elimination
D
Activity
Question 13 Explanation:
Eating is the most important of these because food in the stomach must be a consideration.
Question 14
The interaction of one drug increased by the presence of a second drug is known as:
A
Potentiation
B
Addictive effects
C
Antagonism
D
Synergism
Question 14 Explanation:
Potentiation occurs when the action of one drug is increased by the action of another. Think of two words potentiate and potential together. The potential of one drug is higher when a second drug is added to it.
Question 15
Central venous access devices are beneficial in pediatric therapy because:
A
They are difficult to see.
B
They cannot be dislodged.
C
Use of the arms is not restricted.
D
They don’t frighten children.
Question 15 Explanation:
The child can move his extremities and function in a normal fashion. This lessens stress associated with position restriction and promotes normal activity. Fear may not be eliminated. All lines can be dislodged. Even small catheters can be readily seen.
Question 16
When considering the pharmacotherapeutic effects of drugs administered to clients, the nurse considers which property of most importance:
A
Efficacy
B
Interaction with other drugs
C
Potency
D
Toxicity
Question 16 Explanation:
In pharmacology, efficacy is the maximum response achievable from a drug.
Question 17
As a knowledgeable nurse, you know that the following are part of the five rights except:
A
Right dose
B
Right route
C
Right drug
D
Right room
Question 17 Explanation:
Right room is not one of the five rights.The five rights are right client, route, dose, drug, and time.
Question 18
The client’s ability to take oral medications will be hindered by:
A
Age
B
Dental caries
C
Dysphagia
D
Lifestyle
Question 18 Explanation:
Dysphagia is difficulty swallowing. This would make administration of oral medications impossible. Other choices do not impair ingestion.
Question 19
The volume of SC medication must be no more than:
A
0.5 mL
B
1.0 mL
C
1.5 mL
D
3.0 mL
Question 19 Explanation:
The maximum amount of fluid that can be injected into the SC space is 1.0 mL.
Question 20
When a drug binds to a receptor to produce a pharmacologic effect, the drug may be called a(n):
A
Agonist
B
Antagonist
C
Blocker
D
Accelerator
Question 20 Explanation:
An agonist is the action described in the stem. B and C are synonymous. ELiminate choice D because there is no such action described in drug nomenclature.
Once you are finished, click the button below. Any items you have not completed will be marked incorrect.
Get Results
There are 20 questions to complete.
←
List
→
Return
Shaded items are complete.
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
End
Return
You have completed
questions
question
Your score is
Correct
Wrong
Partial-Credit
You have not finished your quiz. If you leave this page, your progress will be lost.
Correct Answer
You Selected
Not Attempted
Final Score on Quiz
Attempted Questions Correct
Attempted Questions Wrong
Questions Not Attempted
Total Questions on Quiz
Question Details
Results
Date
Score
Hint
Time allowed
minutes
seconds
Time used
Answer Choice(s) Selected
Question Text
All done
Need more practice!
Keep trying!
Not bad!
Good work!
Perfect!
Exam Mode
Exam Mode – Questions and choices are randomly arranged, time limit of 1min per question, answers and grade will be revealed after finishing the exam.
NCLEX Practice Exam for Pharmacology Essential Principles and Drug Administration (EM)
Choose the letter of the correct answer. You got 20 minutes to finish the exam .Good luck!
Start
Congratulations - you have completed NCLEX Practice Exam for Pharmacology Essential Principles and Drug Administration (EM).
You scored %%SCORE%% out of %%TOTAL%%.
Your performance has been rated as %%RATING%%
Your answers are highlighted below.
Question 1
When two drugs given together have an effect equal to the sum of their respective effects, the interaction is known as:
A
Potentiated
B
Antagonized
C
Agonist
D
Additive
Question 1 Explanation:
An addictive effect occurs when two drugs are given together and their effects is equal to the sum of their respective effects.
Question 2
Central venous access devices are beneficial in pediatric therapy because:
A
They are difficult to see.
B
They cannot be dislodged.
C
Use of the arms is not restricted.
D
They don’t frighten children.
Question 2 Explanation:
The child can move his extremities and function in a normal fashion. This lessens stress associated with position restriction and promotes normal activity. Fear may not be eliminated. All lines can be dislodged. Even small catheters can be readily seen.
Question 3
Which of the following muscles is a possible site for IM injections?
A
Outer aspect of the hip
B
Shoulder
C
Vastus gluteus
D
Vastus lateralis
Question 3 Explanation:
Possible injection sites for IM administration include ventrogluteal, deltoid, dorsogluteal, vastus lateralis, and rectus femoris.
Question 4
Absorption, distribution, and excretion may be increased by which of the following diseases?
A
Hyperthyroidism
B
Renal insufficiency
C
Liver disease
D
Hypothyroidism
Question 4 Explanation:
Diseases that speed up metabolism, such as hyperthyroidism, will increase absorption, distribution, and elimination. B, C, and D are incorrect because diseases that decrease metabolism, such as hypothyroidism, renal insufficiency, and liver disease, will slow these metabolic processes.
Question 5
An unexpected effect of the drug is known as a(n):
A
Side effect
B
Adverse effect
C
Toxic reaction
D
Allergic reaction
Question 5 Explanation:
An adverse reaction is a harmful and unexpected reaction. A side effect is expected and predictable. C and D are incorrect because a toxic reaction is a type of adverse reaction.
Question 6
When deciding on what time of day to give medications, the nurse pays closest attention to the client’s habits regarding:
A
Eating
B
Sleeping
C
Elimination
D
Activity
Question 6 Explanation:
Eating is the most important of these because food in the stomach must be a consideration.
Question 7
Distribution is affected by:
A
Biotransformation
B
Excretion
C
Protein binding
D
Lipid binding
Question 7 Explanation:
Distribution depends on protein binding as well as circulation. Biotransformation is the act of metabolizing the drug. Excretion describes the act of eliminating the drug. There is no such thing as lipid binding.
Question 8
When considering the pharmacotherapeutic effects of drugs administered to clients, the nurse considers which property of most importance:
A
Efficacy
B
Interaction with other drugs
C
Potency
D
Toxicity
Question 8 Explanation:
In pharmacology, efficacy is the maximum response achievable from a drug.
Question 9
The client’s ability to take oral medications will be hindered by:
A
Age
B
Dental caries
C
Dysphagia
D
Lifestyle
Question 9 Explanation:
Dysphagia is difficulty swallowing. This would make administration of oral medications impossible. Other choices do not impair ingestion.
Question 10
When performing an assessment to determine which medications can be used, which of the following elements is most important?
A
Physical examination
B
Allergies
C
Presence of illness
D
Weight
Question 10 Explanation:
Allergies must be determined so that the nurse does not administer a drug that would be dangerous to the client.
Question 11
When performing an assessment about medication, the drug history should include:
A
Complete vital signs
B
Client’s goal of therapy
C
Reason for medication
D
Administration of OTC medications
Question 11 Explanation:
The nurse should determine if the client is taking any other medications, especially OTC medications because their effects are often minimized. Other choices are important part of assessment, but choice D is the most accurate answer.
Question 12
Which of the following will determine nursing interventions for a client on medication?
A
Assessment
B
Diagnoses
C
Implementation
D
Evaluation
Question 12 Explanation:
The nursing diagnosis is the conclusion derived from the assessment, and it is the component of the nursing process that drives the interventions.
Question 13
The interaction of one drug increased by the presence of a second drug is known as:
A
Potentiation
B
Addictive effects
C
Antagonism
D
Synergism
Question 13 Explanation:
Potentiation occurs when the action of one drug is increased by the action of another. Think of two words potentiate and potential together. The potential of one drug is higher when a second drug is added to it.
Question 14
When a drug binds to a receptor to produce a pharmacologic effect, the drug may be called a(n):
A
Agonist
B
Antagonist
C
Blocker
D
Accelerator
Question 14 Explanation:
An agonist is the action described in the stem. B and C are synonymous. ELiminate choice D because there is no such action described in drug nomenclature.
Question 15
As a knowledgeable nurse, you know that the following are part of the five rights except:
A
Right dose
B
Right route
C
Right drug
D
Right room
Question 15 Explanation:
Right room is not one of the five rights.The five rights are right client, route, dose, drug, and time.
Question 16
The volume of SC medication must be no more than:
A
0.5 mL
B
1.0 mL
C
1.5 mL
D
3.0 mL
Question 16 Explanation:
The maximum amount of fluid that can be injected into the SC space is 1.0 mL.
Question 17
The name selected by the original manufacturer based on the chemical structure of the drug is the:
A
Chemical name
B
Drug name
C
Generic name
D
Trade name
Question 17 Explanation:
The chemical name is the chemical name is the chemical structure of the compound. The trade name is a proprietary name owned by the company that creates and registers it. The drug name does not exist.
Question 18
Safety of a drug is determined by the degree between:
A
Therapeutic and toxic doses
B
Potency and efficacy
C
Subtherapeutic and toxic levels
D
Side and adverse effects
Question 18 Explanation:
Safety is determined by the degree between therapeutic and toxic doses. Potency and efficacy are not related to safety. Subtherapeutic levels are not part of safety determinations because if a drug is subtherapeutic it does not exert any desired effect. Side effects are expected, and adverse effects are often the result of toxicity.
Question 19
When a drug is 50% protein bound, it means that:
A
50% of the drug destroys protein
B
50% of the dose is at work
C
50% of the drug is excreted in the kidneys
D
Protein must be restricted in the diet
Question 19 Explanation:
The percentage of drug NOT protein bound is the amount of drug that is free to exert its effect on the body’s issues. A, C, and D are incorrect because protein binding has nothing to do with the destruction of protein, drug excretion, or protein in the diet. Note that the concept of “50% bound” literally means that 50% is BOUND or connected to protein. This means that the remaining 50% is available.
Question 20
The extent to which drug is absorbed and transported to target tissue is known as:
A
Steady-state accumulation
B
Therapeutic drug levels
C
Bioavailability
D
Distribution
Question 20 Explanation:
Bioavailability is the extent to which a drug is absorbed and transported to target tissue. Steady-state accumulation means that the amount of drug present is sufficient to exert its therapeutic effect. Therapeutic drug levels are serum blood tests used to measure the amount of circulating drug present. Distribution is the process by which drugs are transported to tissues.
Once you are finished, click the button below. Any items you have not completed will be marked incorrect.
Get Results
There are 20 questions to complete.
←
List
→
Return
Shaded items are complete.
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
End
Return
You have completed
questions
question
Your score is
Correct
Wrong
Partial-Credit
You have not finished your quiz. If you leave this page, your progress will be lost.
Correct Answer
You Selected
Not Attempted
Final Score on Quiz
Attempted Questions Correct
Attempted Questions Wrong
Questions Not Attempted
Total Questions on Quiz
Question Details
Results
Date
Score
Hint
Time allowed
minutes
seconds
Time used
Answer Choice(s) Selected
Question Text
All done
Need more practice!
Keep trying!
Not bad!
Good work!
Perfect!
Text Mode
Text Mode – Text version of the exam
1. The name selected by the original manufacturer based on the chemical structure of the drug is the:
Chemical name
Drug name
Generic name
Trade name
2. The interaction of one drug increased by the presence of a second drug is known as:
Potentiation
Addictive effects
Antagonism
Synergism
3. When two drugs given together have an effect equal to the sum of their respective effects, the interaction is known as:
Potentiated
Antagonized
Agonist
Additive
4. Absorption, distribution, and excretion may be increased by which of the following diseases?
Hyperthyroidism
Renal insufficiency
Liver disease
Hypothyroidism
5. When a drug is 50% protein bound, it means that:
50% of the drug destroys protein
50% of the dose is at work
50% of the drug is excreted in the kidneys
Protein must be restricted in the diet
6. Safety of a drug is determined by the degree between:
Therapeutic and toxic doses
Potency and efficacy
Subtherapeutic and toxic levels
Side and adverse effects
7. When a drug binds to a receptor to produce a pharmacologic effect, the drug may be called a(n):
Agonist
Antagonist
Blocker
Accelerator
8. The extent to which drug is absorbed and transported to target tissue is known as:
Steady-state accumulation
Therapeutic drug levels
Bioavailability
Distribution
9. Distribution is affected by:
Biotransformation
Excretion
Protein binding
Lipid binding
10. An unexpected effect of the drug is known as a(n):
Side effect
Adverse effect
Toxic reaction
Allergic reaction
11. As a knowledgeable nurse, you know that the following are part of the five rights except:
Right dose
Right route
Right drug
Right room
12. When performing an assessment about medication, the drug history should include:
Complete vital signs
Client’s goal of therapy
Reason for medication
Administration of OTC medications
13. The volume of SC medication must be no more than:
0.5 mL
1.0 mL
1.5 mL
3.0 mL
14. Which of the following muscles is a possible site for IM injections?
Outer aspect of the hip
Shoulder
Vastus gluteus
Vastus lateralis
15. When deciding on what time of day to give medications, the nurse pays closest attention to the client’s habits regarding:
Eating
Sleeping
Elimination
Activity
16. The client’s ability to take oral medications will be hindered by:
Age
Dental caries
Dysphagia
Lifestyle
17. Which of the following will determine nursing interventions for a client on medication?
Assessment
Diagnoses
Implementation
Evaluation
18. When performing an assessment to determine which medications can be used, which of the following elements is most important?
Physical examination
Allergies
Presence of illness
Weight
19. Central venous access devices are beneficial in pediatric therapy because:
They are difficult to see.
They cannot be dislodged.
Use of the arms is not restricted.
They don’t frighten children.
20. When considering the pharmacotherapeutic effects of drugs administered to clients, the nurse considers which property of most importance:
Efficacy
Interaction with other drugs
Potency
Toxicity
Answers and Rationale
Answer: C. Generic name. The chemical name is the chemical name is the chemical structure of the compound. The trade name is a proprietary name owned by the company that creates and registers it. The drug name does not exist.
Answer: A. Potentiation. Potentiation occurs when the action of one drug is increased by the action of another. Think of two words potentiate and potential together. The potential of one drug is higher when a second drug is added to it.
Answer: D. Additive. An addictive effect occurs when two drugs are given together and their effects is equal to the sum of their respective effects.
Answer: A. Hyperthyroidism. Diseases that speed up metabolism, such as hyperthyroidism, will increase absorption, distribution, and elimination. B, C, and D are incorrect because diseases that decrease metabolism, such as hypothyroidism, renal insufficiency, and liver disease, will slow these metabolic processes.
Answer: B. 50% of the dose is at work. The percentage of drug NOT protein bound is the amount of drug that is free to exert its effect on the body’s issues. A, C, and D are incorrect because protein binding has nothing to do with the destruction of protein, drug excretion, or protein in the diet. Note that the concept of “50% bound” literally means that 50% is BOUND or connected to protein. This means that the remaining 50% is available.
Answer: A. Therapeutic and toxic doses. Safety is determined by the degree between therapeutic and toxic doses. Potency and efficacy are not related to safety. Subtherapeutic levels are not part of safety determinations because if a drug is subtherapeutic it does not exert any desired effect. Side effects are expected, and adverse effects are often the result of toxicity.
Answer: A. Agonist. An agonist is the action described in the stem. B and C are synonymous. ELiminate choice D because there is no such action described in drug nomenclature.
Answer: C. Bioavailability. Bioavailability is the extent to which a drug is absorbed and transported to target tissue. Steady-state accumulation means that the amount of drug present is sufficient to exert its therapeutic effect. Therapeutic drug levels are serum blood tests used to measure the amount of circulating drug present. Distribution is the process by which drugs are transported to tissues.
Answer: C. Protein binding. Distribution depends on protein binding as well as circulation. Biotransformation is the act of metabolizing the drug. Excretion describes the act of eliminating the drug. There is no such thing as lipid binding.
Answer: B. Adverse effect. An adverse reaction is a harmful and unexpected reaction. A side effect is expected and predictable. C and D are incorrect because a toxic reaction is a type of adverse reaction.
Answer: D. Right room. Right room is not one of the five rights.The five rights are right client, route, dose, drug, and time.
Answer: D. Administration of OTC medications. The nurse should determine if the client is taking any other medications, especially OTC medications because their effects are often minimized. Other choices are important part of assessment, but choice D is the most accurate answer.
Answer: B. 1.0 mL. The maximum amount of fluid that can be injected into the SC space is 1.0 mL.
Answer: D. Vastus lateralis. Possible injection sites for IM administration include ventrogluteal, deltoid, dorsogluteal, vastus lateralis, and rectus femoris.
Answer: A. Eating. Eating is the most important of these because food in the stomach must be a consideration.
Answer: C. Dysphagia. Dysphagia is difficulty swallowing. This would make administration of oral medications impossible. Other choices do not impair ingestion.
Answer: B. Diagnoses. The nursing diagnosis is the conclusion derived from the assessment, and it is the component of the nursing process that drives the interventions.
Answer: B. Allergies. Allergies must be determined so that the nurse does not administer a drug that would be dangerous to the client.
Answer: C. Use of the arms is not restricted.. The child can move his extremities and function in a normal fashion. This lessens stress associated with position restriction and promotes normal activity. Fear may not be eliminated. All lines can be dislodged. Even small catheters can be readily seen.
Answer: A. Efficacy. In pharmacology, efficacy is the maximum response achievable from a drug.